
TEDxHarvardSquare 2026
Andrea Choe
Co-Founder & CEO Holoclara
Signals in the noise (lessons from a worm)
Dr. Andrea Choe is the co-founder and CEO of Holoclara, the first company to create safe, orally available worm-derived therapies. While pursuing her doctorate at the California Institute of Technology (Caltech), she uncovered a unique pheromone language shared by roundworms. Dr. Choe’s research, including her discovery of novel molecules derived from worms that blocked disease formation in animal models of allergic and autoimmune disease, has become the foundation of Holoclara’s technology. She is a winner of the Emerging Women Founders in Biotech Award.





